Useful if the topic is complex and to attract attention.

http://epicentro.instructure.com/eportfolios/2133/Geneza_Pharmaceuticals_Gp_Sust_270__Geneza_Pharmaceuticals__Injectable_Steroids
http://courses.ecornell.com/eportfolios/24202/Novorapid_Msg_Effects__Novo_Nordisk__Diabetes

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This data is a great source for deciding how to optimize your future newsletters , since it tells you which elements of your newsletter can be tweaked.